Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM120948'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM120948 (US8716285, 5) Show SMILES ONC(=O)c1ccc2CCC(Cc2c1)Nc1ccccn1 Show InChI InChI=1S/C16H17N3O2/c20-16(19-21)12-5-4-11-6-7-14(10-13(11)9-12)18-15-3-1-2-8-17-15/h1-5,8-9,14,21H,6-7,10H2,(H,17,18)(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
Roche Pharmaceutical Research and Early Development Curated by ChEMBL					Assay Description Inhibition of HDAC6 in human A549 cells assessed as tubulin acetylation after 17 to 18 hrs by cytoblot assay				J Med Chem 57: 8026-34 (2014) Article DOI: 10.1021/jm5008962 BindingDB Entry DOI: 10.7270/Q29C700V
					More data for this Ligand-Target Pair