BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM50247591'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50247591
PNG
(CHEMBL4096377)
Show SMILES ONC(=O)\C=C\c1ccc(CNc2cccc3cccnc23)cc1
Show InChI InChI=1S/C19H17N3O2/c23-18(22-24)11-10-14-6-8-15(9-7-14)13-21-17-5-1-3-16-4-2-12-20-19(16)17/h1-12,21,24H,13H2,(H,22,23)/b11-10+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 42n/an/an/an/an/an/a



Taipei Medical University

Curated by ChEMBL


Assay Description
Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...

J Med Chem 61: 905-917 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01404
BindingDB Entry DOI: 10.7270/Q2Q81GGB
More data for this
Ligand-Target Pair