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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM50263449'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50263449
PNG
(CHEMBL4101480)
Show SMILES COc1ccc2n(Cc3ccc(cc3)C(=O)NO)c3CN4CC(c3c2c1)C(=O)N(C)C4
Show InChI InChI=1S/C23H24N4O4/c1-25-13-26-11-18(23(25)29)21-17-9-16(31-2)7-8-19(17)27(20(21)12-26)10-14-3-5-15(6-4-14)22(28)24-30/h3-9,18,30H,10-13H2,1-2H3,(H,24,28)
PDB
MMDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
 0.160n/an/an/an/an/an/an/an/a



Institute of Pharmacy, Faculty of Chemistry and Pharmacy , University of Regensburg , 93040 Regensburg , Germany.

Curated by ChEMBL


Assay Description
Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus-infected Sf9 insect cells using RHKK(Ac)AMC as subst...

J Med Chem 61: 3454-3477 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01593
BindingDB Entry DOI: 10.7270/Q24B33S0
More data for this
Ligand-Target Pair