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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM50263484'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50263484
PNG
(CHEMBL4092802)
Show SMILES CN1C(=O)C2CN(Cc3c2c2cc(O)ccc2n3Cc2ccc(cc2)C(=O)NO)C1=O
Show InChI InChI=1S/C22H20N4O5/c1-24-21(29)16-10-25(22(24)30)11-18-19(16)15-8-14(27)6-7-17(15)26(18)9-12-2-4-13(5-3-12)20(28)23-31/h2-8,16,27,31H,9-11H2,1H3,(H,23,28)
PDB
MMDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
 0.420n/an/an/an/an/an/an/an/a



Institute of Pharmacy, Faculty of Chemistry and Pharmacy , University of Regensburg , 93040 Regensburg , Germany.

Curated by ChEMBL


Assay Description
Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus-infected Sf9 insect cells using RHKK(Ac)AMC as subst...

J Med Chem 61: 3454-3477 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01593
BindingDB Entry DOI: 10.7270/Q24B33S0
More data for this
Ligand-Target Pair