Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM50382632'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50382632 (CHEMBL2023529) Show SMILES COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](NCc6ccc(cc6)-c6cn(CCCCCCC(=O)NO)nn6)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O |r| Show InChI InChI=1S/C43H49N5O12/c1-22-38(51)28(44-20-24-12-14-25(15-13-24)29-21-48(47-45-29)16-7-5-4-6-11-32(50)46-57)17-33(59-22)60-31-19-43(56,23(2)49)18-27-35(31)42(55)37-36(40(27)53)39(52)26-9-8-10-30(58-3)34(26)41(37)54/h8-10,12-15,21-22,28,31,33,38,44,51,53,55-57H,4-7,11,16-20H2,1-3H3,(H,46,50)/t22-,28-,31-,33-,38+,43-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC6 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis				J Med Chem 55: 1465-77 (2012) Article DOI: 10.1021/jm200799p BindingDB Entry DOI: 10.7270/Q24F1RRP
					More data for this Ligand-Target Pair