Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM50293358'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50293358 (CHEMBL556332 | N-Hydroxy-E-3-(4'-hydroxybiphenyl-4...) Show SMILES ONC(=O)\C=C\c1ccc(cc1)-c1ccc(O)cc1 Show InChI InChI=1S/C15H13NO3/c17-14-8-6-13(7-9-14)12-4-1-11(2-5-12)3-10-15(18)16-19/h1-10,17,19H,(H,16,18)/b10-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Milano Curated by ChEMBL					Assay Description Inhibition of human HDAC8 using fluorogenic tetrapeptide RHKKAc as substrate				Eur J Med Chem 79: 251-9 (2014) Article DOI: 10.1016/j.ejmech.2014.04.021 BindingDB Entry DOI: 10.7270/Q2V989KV
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50293358 (CHEMBL556332 | N-Hydroxy-E-3-(4'-hydroxybiphenyl-4...) Show SMILES ONC(=O)\C=C\c1ccc(cc1)-c1ccc(O)cc1 Show InChI InChI=1S/C15H13NO3/c17-14-8-6-13(7-9-14)12-4-1-11(2-5-12)3-10-15(18)16-19/h1-10,17,19H,(H,16,18)/b10-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Homo sapiens (human) HDAC8				Citation and Details Article DOI: 10.1007/s00044-011-9571-y BindingDB Entry DOI: 10.7270/Q2KH0R79
					More data for this Ligand-Target Pair