Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM50351944'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50351944 (CHEMBL1822043) Show SMILES CC(C)CCc1c(O)c(CCC(=O)NO)ccc1OCCCCCCCC(=O)NO Show InChI InChI=1S/C22H36N2O6/c1-16(2)9-12-18-19(13-10-17(22(18)27)11-14-21(26)24-29)30-15-7-5-3-4-6-8-20(25)23-28/h10,13,16,27-29H,3-9,11-12,14-15H2,1-2H3,(H,23,25)(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of human HDAC8 using Boc-Lys(TFA)-AMC as substrate incubated 30 mins before substrate addition measured after 30 mins post substrate addit...				Eur J Med Chem 46: 4042-9 (2011) Article DOI: 10.1016/j.ejmech.2011.06.002 BindingDB Entry DOI: 10.7270/Q2ZS2WWD
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