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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 9' and Ligand = 'BDBM50044635'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 9


(Homo sapiens (Human))		BDBM50044635
PNG
(CHEMBL3309291)
Show SMILES CC1(C)CC(=O)Nc2ccc(cc12)C(=O)NCc1ccc(\C=C\C(=O)NO)cc1
Show InChI InChI=1S/C22H23N3O4/c1-22(2)12-20(27)24-18-9-8-16(11-17(18)22)21(28)23-13-15-5-3-14(4-6-15)7-10-19(26)25-29/h3-11,29H,12-13H2,1-2H3,(H,23,28)(H,24,27)(H,25,26)/b10-7+
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n/an/a 37n/an/an/an/an/an/a



Nippon Pharmaceutical Chemicals Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human HDAC9 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay

Bioorg Med Chem 22: 3720-31 (2014)


Article DOI: 10.1016/j.bmc.2014.05.001
BindingDB Entry DOI: 10.7270/Q24T6M0V
More data for this
Ligand-Target Pair