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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone lysine demethylase PHF8' and Ligand = 'BDBM276054'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone lysine demethylase PHF8


(Homo sapiens (Human))		BDBM276054
PNG
(4-[2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]pyri...)
Show SMILES N#Cc1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1
Show InChI InChI=1S/C23H17N7/c24-13-21-23(28-29-27-21)18-8-10-25-20(12-18)22-14-30(15-26-22)11-9-17-6-3-5-16-4-1-2-7-19(16)17/h1-8,10,12,14-15H,9,11H2,(H,27,28,29)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 300n/an/an/an/an/an/a



GSK



Assay Description
PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...

Bioorg Med Chem Lett 17: 1584-9 (2007)


BindingDB Entry DOI: 10.7270/Q2FT8PBQ
More data for this
Ligand-Target Pair