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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone lysine demethylase PHF8' and Ligand = 'BDBM276064'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone lysine demethylase PHF8


(Homo sapiens (Human))		BDBM276064
PNG
(2-[1-[[2-fluoro-3-(trifluoromethoxy)phenyl]methyl]...)
Show SMILES Fc1c(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)cccc1OC(F)(F)F
Show InChI InChI=1S/C18H12F4N6O/c19-17-12(2-1-3-16(17)29-18(20,21)22)8-28-9-15(24-10-28)13-6-11(4-5-23-13)14-7-25-27-26-14/h1-7,9-10H,8H2,(H,25,26,27)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>500n/an/an/an/an/an/a



GSK



Assay Description
PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...

Bioorg Med Chem Lett 17: 1584-9 (2007)


BindingDB Entry DOI: 10.7270/Q2FT8PBQ
More data for this
Ligand-Target Pair