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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone lysine demethylase PHF8' and Ligand = 'BDBM276084'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone lysine demethylase PHF8


(Homo sapiens (Human))		BDBM276084
PNG
(1-[(3-chlorophenyl)methyl]-4-{1H-[1,2,3]triazolo[4...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc3[nH]nnc3cn2)c1
Show InChI InChI=1S/C15H11ClN6/c16-11-3-1-2-10(4-11)7-22-8-15(18-9-22)12-5-13-14(6-17-12)20-21-19-13/h1-6,8-9H,7H2,(H,19,20,21)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>500n/an/an/an/an/an/a



GSK



Assay Description
PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...

Bioorg Med Chem Lett 17: 1584-9 (2007)


BindingDB Entry DOI: 10.7270/Q2FT8PBQ
More data for this
Ligand-Target Pair