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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone lysine demethylase PHF8' and Ligand = 'BDBM276087'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone lysine demethylase PHF8


(Homo sapiens (Human))		BDBM276087
PNG
(1-(4-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...)
Show SMILES Clc1ccc(cc1)-n1cnc(c1)-c1cc2[nH]nnc2cn1
Show InChI InChI=1S/C14H9ClN6/c15-9-1-3-10(4-2-9)21-7-14(17-8-21)11-5-12-13(6-16-11)19-20-18-12/h1-8H,(H,18,19,20)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>500n/an/an/an/an/an/a



GSK



Assay Description
PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...

Bioorg Med Chem Lett 17: 1584-9 (2007)


BindingDB Entry DOI: 10.7270/Q2FT8PBQ
More data for this
Ligand-Target Pair