Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone-arginine methyltransferase CARM1' and Ligand = 'BDBM50258787'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50258787 ((S)-2-amino-N-(3-(5-(5-(2-methoxyphenyl)-1,3,4-oxa...) Show SMILES COc1ccccc1-c1nnc(o1)-c1cc(nn1-c1cccc(CNC(=O)[C@H](C)N)c1)C(F)(F)F |r| Show InChI InChI=1S/C23H21F3N6O3/c1-13(27)20(33)28-12-14-6-5-7-15(10-14)32-17(11-19(31-32)23(24,25)26)22-30-29-21(35-22)16-8-3-4-9-18(16)34-2/h3-11,13H,12,27H2,1-2H3,(H,28,33)/t13-/m0/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of CARM1 assessed as blockade of histone H3 methylation				Bioorg Med Chem Lett 19: 2924-7 (2009) Article DOI: 10.1016/j.bmcl.2009.04.075 BindingDB Entry DOI: 10.7270/Q24B3170
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