Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone-arginine methyltransferase CARM1' and Ligand = 'BDBM50301072'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50301072 ((R)-1-(4-(2-(2-methoxypyridin-3-yl)-4-methyl-1H-be...) Show SMILES CN[C@H](C)CN1CCC(CC1)c1cc(C)c2nc([nH]c2c1)-c1cccnc1OC |r| Show InChI InChI=1S/C23H31N5O/c1-15-12-18(17-7-10-28(11-8-17)14-16(2)24-3)13-20-21(15)27-22(26-20)19-6-5-9-25-23(19)29-4/h5-6,9,12-13,16-17,24H,7-8,10-11,14H2,1-4H3,(H,26,27)/t16-/m1/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human CARM1 assessed as inhibition of histone3 methylation				Bioorg Med Chem Lett 19: 5063-6 (2009) Article DOI: 10.1016/j.bmcl.2009.07.040 BindingDB Entry DOI: 10.7270/Q2KW5G3W
					More data for this Ligand-Target Pair