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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EHMT1' and Ligand = 'BDBM50268899'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone-lysine N-methyltransferase EHMT1


(Homo sapiens (Human))		BDBM50268899
PNG
(CHEMBL4073147)
Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)C1CCOCC1
Show InChI InChI=1S/C22H33N5O3/c1-26-9-5-15(6-10-26)23-21-17-13-19(28-3)20(29-4)14-18(17)24-22(25-21)27(2)16-7-11-30-12-8-16/h13-16H,5-12H2,1-4H3,(H,23,24,25)
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Article
PubMed
n/an/a 159n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL


Assay Description
Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...

Bioorg Med Chem 25: 4414-4423 (2017)


Article DOI: 10.1016/j.bmc.2017.06.021
BindingDB Entry DOI: 10.7270/Q2X350ZG
More data for this
Ligand-Target Pair