Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human)) | BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of EHMT1 (unknown origin) | Bioorg Med Chem 25: 4579-4594 (2017) Article DOI: 10.1016/j.bmc.2017.06.032 BindingDB Entry DOI: 10.7270/Q2CC135P | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human)) | BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 2.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of EHMT1 (unknown origin) preincubated for 5 mins followed by SAM and biotinylated H3K9 peptide addition measured after 120 mins by HTRF a... | Bioorg Med Chem 25: 4579-4594 (2017) Article DOI: 10.1016/j.bmc.2017.06.032 BindingDB Entry DOI: 10.7270/Q2CC135P | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human)) | BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 5.13E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of methyltransferase activity of EHMT1 (unknown origin)-mediated dimethylation of a biotinylated histone H3 peptide at lysine-9 by FRET-ba... | ACS Med Chem Lett 5: 293-7 (2014) Article DOI: 10.1021/ml4002503 BindingDB Entry DOI: 10.7270/Q2N58NWS | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |