Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EZH2' and Ligand = 'BDBM50193657'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50193657 (CHEMBL3955994) Show SMILES CC(C)Oc1ccc2CCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1C Show InChI InChI=1S/C21H26N2O3/c1-12(2)26-18-7-6-16-8-9-23(21(25)19(16)15(18)5)11-17-13(3)10-14(4)22-20(17)24/h6-7,10,12H,8-9,11H2,1-5H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...				J Med Chem 59: 8306-25 (2016) Article DOI: 10.1021/acs.jmedchem.6b00515 BindingDB Entry DOI: 10.7270/Q2J1053B
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50193657 (CHEMBL3955994) Show SMILES CC(C)Oc1ccc2CCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1C Show InChI InChI=1S/C21H26N2O3/c1-12(2)26-18-7-6-16-8-9-23(21(25)19(16)15(18)5)11-17-13(3)10-14(4)22-20(17)24/h6-7,10,12H,8-9,11H2,1-5H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex by ITC analysis				J Med Chem 59: 8306-25 (2016) Article DOI: 10.1021/acs.jmedchem.6b00515 BindingDB Entry DOI: 10.7270/Q2J1053B
					More data for this Ligand-Target Pair