BindingDB PrimarySearch

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase SUV39H1' and Ligand = 'BDBM50031317'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone-lysine N-methyltransferase SUV39H1 (Homo sapiens (Human))	BDBM50031317 (CHEMBL3358015) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of SUV39H1 (unknown origin) incubated for 15 mins before addition of biotinylated peptide H3 (1 to 21) and SAM by methylation assay				J Med Chem 57: 9028-41 (2014) Article DOI: 10.1021/jm501134e BindingDB Entry DOI: 10.7270/Q2JD4ZD6
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair