Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Homoserine kinase' and Ligand = 'BDBM85126'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homoserine kinase (Escherichia coli)	BDBM85126 (Thr1 inhibitor, 6) Show SMILES CC1NN(c2nc(cc(O)c12)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C14H12F3N3O/c1-8-12-10(21)7-11(14(15,16)17)18-13(12)20(19-8)9-5-3-2-4-6-9/h2-8,19H,1H3,(H,18,21)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.60E+3	-30.1	n/a	n/a	n/a	n/a	n/a	7.5	37
McMaster University					Assay Description The phosphorylation of L-Hse was monitored by coupling the formation of ADP with pyruvate kinase and lactate dehydrogenase (PK/LDH). The resulting o...				Chembiochem 12: 1179-82 (2011) Article DOI: 10.1002/cbic.201100121 BindingDB Entry DOI: 10.7270/Q24T6GWV
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