Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Hydroxycarboxylic acid receptor 2' and Ligand = 'BDBM50297999'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50297999 ((+/-)-5-(2,5-difluorophenyl)-4,5,6,7-tetrahydro-1H...) Show SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cc(F)ccc1F Show InChI InChI=1S/C14H12F2N2O2/c15-8-2-3-11(16)9(6-8)7-1-4-12-10(5-7)13(14(19)20)18-17-12/h2-3,6-7H,1,4-5H2,(H,17,18)(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serum				Bioorg Med Chem Lett 19: 4768-72 (2009) Article DOI: 10.1016/j.bmcl.2009.06.054 BindingDB Entry DOI: 10.7270/Q2M909M3
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50297999 ((+/-)-5-(2,5-difluorophenyl)-4,5,6,7-tetrahydro-1H...) Show SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cc(F)ccc1F Show InChI InChI=1S/C14H12F2N2O2/c15-8-2-3-11(16)9(6-8)7-1-4-12-10(5-7)13(14(19)20)18-17-12/h2-3,6-7H,1,4-5H2,(H,17,18)(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serum				Bioorg Med Chem Lett 19: 4768-72 (2009) Article DOI: 10.1016/j.bmcl.2009.06.054 BindingDB Entry DOI: 10.7270/Q2M909M3
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50297999 ((+/-)-5-(2,5-difluorophenyl)-4,5,6,7-tetrahydro-1H...) Show SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cc(F)ccc1F Show InChI InChI=1S/C14H12F2N2O2/c15-8-2-3-11(16)9(6-8)7-1-4-12-10(5-7)13(14(19)20)18-17-12/h2-3,6-7H,1,4-5H2,(H,17,18)(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in presence of 5% human serum				Bioorg Med Chem Lett 19: 4768-72 (2009) Article DOI: 10.1016/j.bmcl.2009.06.054 BindingDB Entry DOI: 10.7270/Q2M909M3
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50297999 ((+/-)-5-(2,5-difluorophenyl)-4,5,6,7-tetrahydro-1H...) Show SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cc(F)ccc1F Show InChI InChI=1S/C14H12F2N2O2/c15-8-2-3-11(16)9(6-8)7-1-4-12-10(5-7)13(14(19)20)18-17-12/h2-3,6-7H,1,4-5H2,(H,17,18)(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 19: 4768-72 (2009) Article DOI: 10.1016/j.bmcl.2009.06.054 BindingDB Entry DOI: 10.7270/Q2M909M3
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50297999 ((+/-)-5-(2,5-difluorophenyl)-4,5,6,7-tetrahydro-1H...) Show SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cc(F)ccc1F Show InChI InChI=1S/C14H12F2N2O2/c15-8-2-3-11(16)9(6-8)7-1-4-12-10(5-7)13(14(19)20)18-17-12/h2-3,6-7H,1,4-5H2,(H,17,18)(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 19: 4768-72 (2009) Article DOI: 10.1016/j.bmcl.2009.06.054 BindingDB Entry DOI: 10.7270/Q2M909M3
					More data for this Ligand-Target Pair