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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM271463'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM271463
PNG
(2-(4-hydroxy-1-methyl-6-(naphthalen-2-yloxy)-2-oxo...)
Show SMILES Cn1c2ccc(Oc3ccc4ccccc4c3)cc2c(O)c(C(=O)NCC(O)=O)c1=O
Show InChI InChI=1S/C23H18N2O6/c1-25-18-9-8-16(31-15-7-6-13-4-2-3-5-14(13)10-15)11-17(18)21(28)20(23(25)30)22(29)24-12-19(26)27/h2-11,28H,12H2,1H3,(H,24,29)(H,26,27)
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US Patent
n/an/an/an/a 2.52E+3n/an/an/an/a



SUNSHINE LAKE PHARMA CO., LTD.

US Patent


Assay Description
The activities of compounds of the invention in inducing erythropoietin (EPO) production were assessed by using human live cancer cell strain Hep3B (...


US Patent US10065928 (2018)


BindingDB Entry DOI: 10.7270/Q2DB83WQ
More data for this
Ligand-Target Pair