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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50172340'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50172340
PNG
(1-[1-(5-Methoxy-2,2-dimethyl-2H-chromen-6-yl)-ethy...)
Show SMILES COc1c(ccc2OC(C)(C)C=Cc12)C(C)n1cnc2ncccc12 |c:11|
Show InChI InChI=1S/C20H21N3O2/c1-13(23-12-22-19-16(23)6-5-11-21-19)14-7-8-17-15(18(14)24-4)9-10-20(2,3)25-17/h5-13H,1-4H3
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Article
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n/an/an/an/a 3.50E+4n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Effective concentration to inhibit production of hypoxia inducible factor 1-alpha protein


J Med Chem 48: 5613-38 (2005)


Article DOI: 10.1021/jm050524f
BindingDB Entry DOI: 10.7270/Q2V988V1
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50172340
PNG
(1-[1-(5-Methoxy-2,2-dimethyl-2H-chromen-6-yl)-ethy...)
Show SMILES COc1c(ccc2OC(C)(C)C=Cc12)C(C)n1cnc2ncccc12 |c:11|
Show InChI InChI=1S/C20H21N3O2/c1-13(23-12-22-19-16(23)6-5-11-21-19)14-7-8-17-15(18(14)24-4)9-10-20(2,3)25-17/h5-13H,1-4H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 3.50E+4n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Effective concentration to inhibit production of hypoxia inducible factor 1-alpha protein


J Med Chem 48: 5613-38 (2005)


Article DOI: 10.1021/jm050524f
BindingDB Entry DOI: 10.7270/Q2V988V1
More data for this
Ligand-Target Pair