Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50222818'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50222818 (2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...) Show SMILES NC(=O)c1ccnc(NC(=O)COc2ccc(cc2)C23CC4CC(CC(C4)C2)C3)c1 |TLB:16:19:22:26.24.25,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25| Show InChI InChI=1S/C24H27N3O3/c25-23(29)18-5-6-26-21(10-18)27-22(28)14-30-20-3-1-19(2-4-20)24-11-15-7-16(12-24)9-17(8-15)13-24/h1-6,10,15-17H,7-9,11-14H2,(H2,25,29)(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Molecular Cancer Research Center Curated by ChEMBL					Assay Description Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assay				Bioorg Med Chem Lett 17: 6305-10 (2007) Article DOI: 10.1016/j.bmcl.2007.09.005 BindingDB Entry DOI: 10.7270/Q2PR7VQT
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50222818 (2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...) Show SMILES NC(=O)c1ccnc(NC(=O)COc2ccc(cc2)C23CC4CC(CC(C4)C2)C3)c1 |TLB:16:19:22:26.24.25,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25| Show InChI InChI=1S/C24H27N3O3/c25-23(29)18-5-6-26-21(10-18)27-22(28)14-30-20-3-1-19(2-4-20)24-11-15-7-16(12-24)9-17(8-15)13-24/h1-6,10,15-17H,7-9,11-14H2,(H2,25,29)(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Molecular Cancer Research Center Curated by ChEMBL					Assay Description Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assay				Bioorg Med Chem Lett 17: 6305-10 (2007) Article DOI: 10.1016/j.bmcl.2007.09.005 BindingDB Entry DOI: 10.7270/Q2PR7VQT
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50222818 (2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...) Show SMILES NC(=O)c1ccnc(NC(=O)COc2ccc(cc2)C23CC4CC(CC(C4)C2)C3)c1 |TLB:16:19:22:26.24.25,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25| Show InChI InChI=1S/C24H27N3O3/c25-23(29)18-5-6-26-21(10-18)27-22(28)14-30-20-3-1-19(2-4-20)24-11-15-7-16(12-24)9-17(8-15)13-24/h1-6,10,15-17H,7-9,11-14H2,(H2,25,29)(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Molecular Cancer Research Center Curated by ChEMBL					Assay Description Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assay				Bioorg Med Chem Lett 17: 6305-10 (2007) Article DOI: 10.1016/j.bmcl.2007.09.005 BindingDB Entry DOI: 10.7270/Q2PR7VQT
					More data for this Ligand-Target Pair