Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50226373'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50226373 (1-(4-Amino-phenyl)-3-(3-benzo[1,3]dioxol-5-yl-4-ox...) Show SMILES Nc1ccc(NC(=O)Nc2cccc3-c4[nH]nc(c4C(=O)c23)-c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C24H17N5O4/c25-13-5-7-14(8-6-13)26-24(31)27-16-3-1-2-15-19(16)23(30)20-21(28-29-22(15)20)12-4-9-17-18(10-12)33-11-32-17/h1-10H,11,25H2,(H,28,29)(H2,26,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	214	n/a	n/a	n/a	n/a	n/a	n/a
Gakushuin University Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human HeLa cells expressing HRE-Luc after 12 hrs by luciferase reporter gene assa...				ACS Med Chem Lett 4: 297-301 (2013) Article DOI: 10.1021/ml3004632 BindingDB Entry DOI: 10.7270/Q2R212P9
					More data for this Ligand-Target Pair