Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50226890'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50226890 ((1S,6R)-3-methyl-6-{(1R)-1-methyl-3-[(1R,2R,3R,4S)...) Show SMILES C[C@H](CC[C@@H]1[C@@H](C)[C@@]2(C)CC[C@]1(C)O2)[C@H]1CCC(C)=C[C@H]1O |c:20| Show InChI InChI=1S/C20H34O2/c1-13-6-8-16(18(21)12-13)14(2)7-9-17-15(3)19(4)10-11-20(17,5)22-19/h12,14-18,21H,6-11H2,1-5H3/t14-,15-,16-,17-,18-,19-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi. University Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by cell based luciferase assay				J Med Chem 50: 6299-302 (2007) Article DOI: 10.1021/jm7011062 BindingDB Entry DOI: 10.7270/Q2930SX2
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