Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50329891'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329891 (2-chloro-N-(6-(5-ethyl-4-hydroxy-6-methylpyrimidin...) Show SMILES CCc1c(C)nc([nH]c1=O)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C14H15ClN4O2/c1-3-10-8(2)17-13(19-14(10)21)11-5-4-9(7-16-11)18-12(20)6-15/h4-5,7H,3,6H2,1-2H3,(H,18,20)(H,17,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329891 (2-chloro-N-(6-(5-ethyl-4-hydroxy-6-methylpyrimidin...) Show SMILES CCc1c(C)nc([nH]c1=O)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C14H15ClN4O2/c1-3-10-8(2)17-13(19-14(10)21)11-5-4-9(7-16-11)18-12(20)6-15/h4-5,7H,3,6H2,1-2H3,(H,18,20)(H,17,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair