Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50354117'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50354117 (CHEMBL1836234) Show SMILES CCOc1ccccc1-n1c(CN2CCN(CC2)C(=O)c2ccccc2)nc2ccccc2c1=O |(5.33,2.7,;4,1.93,;2.67,2.69,;2.67,4.24,;4,5.01,;4,6.54,;2.67,7.32,;1.33,6.55,;1.33,5.01,;,4.23,;,2.7,;1.33,1.92,;1.33,.38,;,-.39,;,-1.93,;1.33,-2.7,;2.67,-1.93,;2.67,-.39,;1.33,-4.24,;2.67,-5.01,;,-5.01,;-1.33,-4.24,;-2.67,-5.01,;-2.67,-6.55,;-1.33,-7.32,;,-6.55,;-1.33,1.92,;-2.67,2.69,;-4,1.92,;-5.33,2.69,;-5.33,4.24,;-4,5.01,;-2.67,4.24,;-1.33,5.01,;-1.33,6.54,)| Show InChI InChI=1S/C28H28N4O3/c1-2-35-25-15-9-8-14-24(25)32-26(29-23-13-7-6-12-22(23)28(32)34)20-30-16-18-31(19-17-30)27(33)21-10-4-3-5-11-21/h3-15H,2,16-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assay				Bioorg Med Chem Lett 21: 5239-43 (2011) Article DOI: 10.1016/j.bmcl.2011.07.043 BindingDB Entry DOI: 10.7270/Q2H70G65
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