Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50354119'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50354119 (CHEMBL1836233) Show SMILES CCOc1ccccc1-n1c(CN2CCN(CC2)C(C)=O)nc2ccccc2c1=O |(5.33,1.54,;4,.77,;2.67,1.54,;2.67,3.08,;4,3.85,;4,5.39,;2.67,6.16,;1.33,5.39,;1.33,3.85,;,3.08,;,1.54,;1.33,.77,;1.33,-.77,;,-1.54,;,-3.08,;1.33,-3.85,;2.67,-3.08,;2.67,-1.54,;1.33,-5.39,;2.67,-6.16,;,-6.16,;-1.33,.77,;-2.67,1.54,;-4,.77,;-5.33,1.54,;-5.33,3.08,;-4,3.85,;-2.67,3.08,;-1.33,3.85,;-1.33,5.39,)| Show InChI InChI=1S/C23H26N4O3/c1-3-30-21-11-7-6-10-20(21)27-22(16-25-12-14-26(15-13-25)17(2)28)24-19-9-5-4-8-18(19)23(27)29/h4-11H,3,12-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assay				Bioorg Med Chem Lett 21: 5239-43 (2011) Article DOI: 10.1016/j.bmcl.2011.07.043 BindingDB Entry DOI: 10.7270/Q2H70G65
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