Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50354124'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50354124 (CHEMBL1836237) Show SMILES CCOc1ccccc1-n1c(CN2CCN(Cc3ccccc3)CC2)nc2ccccc2c1=O |(5.33,2.69,;4,1.92,;2.67,2.69,;2.67,4.23,;4,5,;4,6.54,;2.67,7.32,;1.33,6.55,;1.33,5,;,4.23,;,2.69,;1.33,1.92,;1.33,.38,;,-.39,;,-1.93,;1.33,-2.7,;1.33,-4.24,;2.67,-5.01,;2.67,-6.55,;4,-7.32,;5.33,-6.55,;5.33,-5.01,;4,-4.23,;2.67,-1.93,;2.67,-.39,;-1.33,1.92,;-2.67,2.69,;-4,1.92,;-5.33,2.69,;-5.33,4.23,;-4,5,;-2.67,4.23,;-1.33,5.01,;-1.33,6.54,)| Show InChI InChI=1S/C28H30N4O2/c1-2-34-26-15-9-8-14-25(26)32-27(29-24-13-7-6-12-23(24)28(32)33)21-31-18-16-30(17-19-31)20-22-10-4-3-5-11-22/h3-15H,2,16-21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assay				Bioorg Med Chem Lett 21: 5239-43 (2011) Article DOI: 10.1016/j.bmcl.2011.07.043 BindingDB Entry DOI: 10.7270/Q2H70G65
					More data for this Ligand-Target Pair