Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50401029'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50401029 (CHEMBL2205734) Show SMILES Cc1cc(nn1Cc1ccc(C)cc1)-c1nc2cc(ccc2[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H21ClN4/c1-16-3-5-18(6-4-16)15-30-17(2)13-24(29-30)25-27-22-12-9-20(14-23(22)28-25)19-7-10-21(26)11-8-19/h3-14H,15H2,1-2H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of HIF-1alpha in human HCT116 cells under hypoxia condition by HRE-luciferase reporter gene assay				Eur J Med Chem 49: 24-40 (2012) Article DOI: 10.1016/j.ejmech.2012.01.033 BindingDB Entry DOI: 10.7270/Q26D5V4N
					More data for this Ligand-Target Pair