new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Immunoglobulin epsilon Fc receptor' and Ligand = 'BDBM50132438'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Immunoglobulin epsilon Fc receptor


(Homo sapiens (Human))
BDBM50132438
PNG
(2-Oxo-3-[1-[1-(4-oxo-4-piperidin-1-yl-butyl)-1H-in...)
Show SMILES NS(=O)(=O)c1ccc2NC(=O)\C(=C/c3cn(CCCC(=O)N4CCCCC4)c4ccccc34)c2c1
Show InChI InChI=1S/C26H28N4O4S/c27-35(33,34)19-10-11-23-21(16-19)22(26(32)28-23)15-18-17-30(24-8-3-2-7-20(18)24)14-6-9-25(31)29-12-4-1-5-13-29/h2-3,7-8,10-11,15-17H,1,4-6,9,12-14H2,(H,28,32)(H2,27,33,34)/b22-15-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a



Aventis Pharmaceuticals

Curated by ChEMBL


Assay Description
Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT release


Bioorg Med Chem Lett 13: 3111-4 (2003)


BindingDB Entry DOI: 10.7270/Q2ZG6SS7
More data for this
Ligand-Target Pair