Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50303910'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50303910 (4-phenylthiazole-2-thiol | CHEMBL571436) Show SMILES Sc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C9H7NS2/c11-9-10-8(6-12-9)7-4-2-1-3-5-7/h1-6H,(H,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO expressed in HEK293 cells assessed as blockade of tryptophan degradation by HPLC				J Med Chem 53: 1172-89 (2010) Article DOI: 10.1021/jm9014718 BindingDB Entry DOI: 10.7270/Q2BC40G9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50303910 (4-phenylthiazole-2-thiol | CHEMBL571436) Show SMILES Sc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C9H7NS2/c11-9-10-8(6-12-9)7-4-2-1-3-5-7/h1-6H,(H,10,11)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of mouse recombinant IDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLC				J Med Chem 53: 1172-89 (2010) Article DOI: 10.1021/jm9014718 BindingDB Entry DOI: 10.7270/Q2BC40G9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50303910 (4-phenylthiazole-2-thiol | CHEMBL571436) Show SMILES Sc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C9H7NS2/c11-9-10-8(6-12-9)7-4-2-1-3-5-7/h1-6H,(H,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
NAMEDIC-NARILIS, University of Namur, 61 Rue de Bruxelles, 5000 Namur, Belgium; Laboratory of Organic Synthesis and Heterocyclic Chemistry, Department of Chemistry, College of Sciences at Tunis, El M Curated by ChEMBL					Assay Description Inhibition of human IDO1 pre-incubated for 10 mins before L-Trp as substrate addition and measured after 30 mins by colorimetry				Bioorg Med Chem Lett 27: 3607-3610 (2017) Article DOI: 10.1016/j.bmcl.2016.06.052 BindingDB Entry DOI: 10.7270/Q2F1925G
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50303910 (4-phenylthiazole-2-thiol | CHEMBL571436) Show SMILES Sc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C9H7NS2/c11-9-10-8(6-12-9)7-4-2-1-3-5-7/h1-6H,(H,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
NAMEDIC-NARILIS, University of Namur, 61 Rue de Bruxelles, 5000 Namur, Belgium; Laboratory of Organic Synthesis and Heterocyclic Chemistry, Department of Chemistry, College of Sciences at Tunis, El M Curated by ChEMBL					Assay Description Inhibition of human IDO1 pre-incubated for 10 mins before L-Trp as substrate addition and measured after 30 mins by colorimetry				Bioorg Med Chem Lett 27: 3607-3610 (2017) Article DOI: 10.1016/j.bmcl.2016.06.052 BindingDB Entry DOI: 10.7270/Q2F1925G
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50303910 (4-phenylthiazole-2-thiol | CHEMBL571436) Show SMILES Sc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C9H7NS2/c11-9-10-8(6-12-9)7-4-2-1-3-5-7/h1-6H,(H,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AI				J Med Chem 53: 1172-89 (2010) Article DOI: 10.1021/jm9014718 BindingDB Entry DOI: 10.7270/Q2BC40G9
					More data for this Ligand-Target Pair