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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor I receptor' and Ligand = 'BDBM50340134'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor I receptor


(Homo sapiens (Human))
BDBM50340134
PNG
(CHEMBL1760047 | N4-(pyridin-2-yl)-N2-(3,4,5-trimet...)
Show SMILES COc1cc(Nc2nccc(Nc3ccccn3)n2)cc(OC)c1OC
Show InChI InChI=1S/C18H19N5O3/c1-24-13-10-12(11-14(25-2)17(13)26-3)21-18-20-9-7-16(23-18)22-15-6-4-5-8-19-15/h4-11H,1-3H3,(H2,19,20,21,22,23)
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MMDB

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n/an/a 251n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of human IGF1R


Bioorg Med Chem Lett 21: 2394-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.075
BindingDB Entry DOI: 10.7270/Q28G8M0D
More data for this
Ligand-Target Pair