Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50059707'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50059707 (7-[(5-Carbamimidoyl-1H-indole-2-carbonyl)-amino]-h...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)C(=O)NCCCCCCC(O)=O Show InChI InChI=1S/C17H22N4O3/c18-16(19)11-6-7-13-12(9-11)10-14(21-13)17(24)20-8-4-2-1-3-5-15(22)23/h6-7,9-10,21H,1-5,8H2,(H3,18,19)(H,20,24)(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonism of fibrinogen binding to a purified human fibrinogen receptor preparation.				J Med Chem 40: 2843-57 (1997) Article DOI: 10.1021/jm970020k BindingDB Entry DOI: 10.7270/Q24M93MS
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50059707 (7-[(5-Carbamimidoyl-1H-indole-2-carbonyl)-amino]-h...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)C(=O)NCCCCCCC(O)=O Show InChI InChI=1S/C17H22N4O3/c18-16(19)11-6-7-13-12(9-11)10-14(21-13)17(24)20-8-4-2-1-3-5-15(22)23/h6-7,9-10,21H,1-5,8H2,(H3,18,19)(H,20,24)(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Vascular endothelial growth factor receptor 2 (KDR)				Bioorg Med Chem Lett 6: 81-86 (1996) Article DOI: 10.1016/0960-894X(95)00563-9 BindingDB Entry DOI: 10.7270/Q2445MGV
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50059707 (7-[(5-Carbamimidoyl-1H-indole-2-carbonyl)-amino]-h...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)C(=O)NCCCCCCC(O)=O Show InChI InChI=1S/C17H22N4O3/c18-16(19)11-6-7-13-12(9-11)10-14(21-13)17(24)20-8-4-2-1-3-5-15(22)23/h6-7,9-10,21H,1-5,8H2,(H3,18,19)(H,20,24)(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of the platelet GPIIb-IIIa receptor measured as ability to attenuate ADP-induced (fibrinogen-mediated) platelet aggregation in human plate...				J Med Chem 40: 2843-57 (1997) Article DOI: 10.1021/jm970020k BindingDB Entry DOI: 10.7270/Q24M93MS
					More data for this Ligand-Target Pair