Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50062790'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50062790 (((S)-4-Carboxymethyl-1-{2-[(4-guanidinomethyl-cycl...) Show SMILES NC(=N)NCC1CCC(CC1)C(=O)NCC(=O)N1CCN(CC(O)=O)C(=O)[C@@H]1CC(O)=O |wD:27.29,(-3.9,-10.25,;-2.57,-11.02,;-2.57,-12.56,;-1.23,-10.25,;.1,-11.02,;1.43,-10.25,;1.45,-8.71,;2.76,-7.94,;4.09,-8.73,;4.11,-10.27,;2.76,-11.04,;5.44,-7.94,;5.42,-6.42,;6.77,-8.73,;8.1,-7.94,;9.43,-8.73,;9.43,-10.27,;10.76,-7.94,;10.76,-6.42,;12.09,-5.63,;13.42,-6.42,;14.75,-5.65,;16.08,-6.42,;17.43,-5.65,;16.08,-7.96,;13.42,-7.94,;14.75,-8.73,;12.09,-8.71,;12.09,-10.25,;13.42,-11.02,;13.42,-12.56,;14.75,-10.25,)| Show InChI InChI=1S/C19H30N6O7/c20-19(21)23-8-11-1-3-12(4-2-11)17(31)22-9-14(26)25-6-5-24(10-16(29)30)18(32)13(25)7-15(27)28/h11-13H,1-10H2,(H,22,31)(H,27,28)(H,29,30)(H4,20,21,23)/t11?,12?,13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Ability to inhibit binding of biotin-labeled human fibrinogen to immobilized fibrinogen receptor purified from human erythroleukemia(HEL) cells.				J Med Chem 41: 489-502 (1998) Article DOI: 10.1021/jm970235u BindingDB Entry DOI: 10.7270/Q2571B4W
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50062790 (((S)-4-Carboxymethyl-1-{2-[(4-guanidinomethyl-cycl...) Show SMILES NC(=N)NCC1CCC(CC1)C(=O)NCC(=O)N1CCN(CC(O)=O)C(=O)[C@@H]1CC(O)=O |wD:27.29,(-3.9,-10.25,;-2.57,-11.02,;-2.57,-12.56,;-1.23,-10.25,;.1,-11.02,;1.43,-10.25,;1.45,-8.71,;2.76,-7.94,;4.09,-8.73,;4.11,-10.27,;2.76,-11.04,;5.44,-7.94,;5.42,-6.42,;6.77,-8.73,;8.1,-7.94,;9.43,-8.73,;9.43,-10.27,;10.76,-7.94,;10.76,-6.42,;12.09,-5.63,;13.42,-6.42,;14.75,-5.65,;16.08,-6.42,;17.43,-5.65,;16.08,-7.96,;13.42,-7.94,;14.75,-8.73,;12.09,-8.71,;12.09,-10.25,;13.42,-11.02,;13.42,-12.56,;14.75,-10.25,)| Show InChI InChI=1S/C19H30N6O7/c20-19(21)23-8-11-1-3-12(4-2-11)17(31)22-9-14(26)25-6-5-24(10-16(29)30)18(32)13(25)7-15(27)28/h11-13H,1-10H2,(H,22,31)(H,27,28)(H,29,30)(H4,20,21,23)/t11?,12?,13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of human platelets by 50% in vitro.				J Med Chem 41: 489-502 (1998) Article DOI: 10.1021/jm970235u BindingDB Entry DOI: 10.7270/Q2571B4W
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50062790 (((S)-4-Carboxymethyl-1-{2-[(4-guanidinomethyl-cycl...) Show SMILES NC(=N)NCC1CCC(CC1)C(=O)NCC(=O)N1CCN(CC(O)=O)C(=O)[C@@H]1CC(O)=O |wD:27.29,(-3.9,-10.25,;-2.57,-11.02,;-2.57,-12.56,;-1.23,-10.25,;.1,-11.02,;1.43,-10.25,;1.45,-8.71,;2.76,-7.94,;4.09,-8.73,;4.11,-10.27,;2.76,-11.04,;5.44,-7.94,;5.42,-6.42,;6.77,-8.73,;8.1,-7.94,;9.43,-8.73,;9.43,-10.27,;10.76,-7.94,;10.76,-6.42,;12.09,-5.63,;13.42,-6.42,;14.75,-5.65,;16.08,-6.42,;17.43,-5.65,;16.08,-7.96,;13.42,-7.94,;14.75,-8.73,;12.09,-8.71,;12.09,-10.25,;13.42,-11.02,;13.42,-12.56,;14.75,-10.25,)| Show InChI InChI=1S/C19H30N6O7/c20-19(21)23-8-11-1-3-12(4-2-11)17(31)22-9-14(26)25-6-5-24(10-16(29)30)18(32)13(25)7-15(27)28/h11-13H,1-10H2,(H,22,31)(H,27,28)(H,29,30)(H4,20,21,23)/t11?,12?,13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of guinea pig platelets by 50% in vitro				J Med Chem 41: 489-502 (1998) Article DOI: 10.1021/jm970235u BindingDB Entry DOI: 10.7270/Q2571B4W
					More data for this Ligand-Target Pair