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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50111426'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50111426
PNG
(6-[(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-ca...)
Show SMILES OC(=O)CCCCCNC(=O)N1CCC2(CCN(C2)c2ccncc2)CC1
Show InChI InChI=1S/C20H30N4O3/c25-18(26)4-2-1-3-10-22-19(27)23-13-7-20(8-14-23)9-15-24(16-20)17-5-11-21-12-6-17/h5-6,11-12H,1-4,7-10,13-16H2,(H,22,27)(H,25,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



COR Therapeutics, Inc.

Curated by ChEMBL


Assay Description
In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.


Bioorg Med Chem Lett 12: 1103-7 (2002)


BindingDB Entry DOI: 10.7270/Q2H131BN
More data for this
Ligand-Target Pair