Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50290317 (4-{1-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihy...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin by 50% in an ELISA test | Bioorg Med Chem Lett 7: 2537-2542 (1997) Article DOI: 10.1016/S0960-894X(97)10014-2 BindingDB Entry DOI: 10.7270/Q2WD40KZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50290317 (4-{1-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihy...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP). | Bioorg Med Chem Lett 7: 2537-2542 (1997) Article DOI: 10.1016/S0960-894X(97)10014-2 BindingDB Entry DOI: 10.7270/Q2WD40KZ | |||||||||||
More data for this Ligand-Target Pair |