Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM187464'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM187464 (US9169252, 65) Show SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(cc1NCC1(F)CCC1)-n1ccc2cc(cnc12)C#N |r| Show InChI InChI=1S/C24H26F2N6O2/c1-23(2,34)19(25)13-30-22(33)17-12-28-20(9-18(17)31-14-24(26)5-3-6-24)32-7-4-16-8-15(10-27)11-29-21(16)32/h4,7-9,11-12,19,34H,3,5-6,13-14H2,1-2H3,(H,28,31)(H,30,33)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	7.2	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...				US Patent US9169252 (2015) BindingDB Entry DOI: 10.7270/Q2MP5235
					More data for this Ligand-Target Pair