Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM188106'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM188106 (US9169252, 637) Show SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(cc1NC12CC(C1)C2)-n1ncc2cc(C#N)c(N)nc12 |r| Show InChI InChI=1S/C23H25FN8O2/c1-22(2,34)17(24)11-28-21(33)15-10-27-18(4-16(15)31-23-5-12(6-23)7-23)32-20-14(9-29-32)3-13(8-25)19(26)30-20/h3-4,9-10,12,17,34H,5-7,11H2,1-2H3,(H2,26,30)(H,27,31)(H,28,33)/t12?,17-,23?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	7.2	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...				US Patent US9169252 (2015) BindingDB Entry DOI: 10.7270/Q2MP5235
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