Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM203706'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM203706 (US9221809, 257) Show SMILES O=c1[nH]c(nc(NCCN2CCCCC2)c1-c1nc2ccccc2s1)N1CCOCC1 Show InChI InChI=1S/C22H28N6O2S/c29-20-18(21-24-16-6-2-3-7-17(16)31-21)19(23-8-11-27-9-4-1-5-10-27)25-22(26-20)28-12-14-30-15-13-28/h2-3,6-7H,1,4-5,8-15H2,(H2,23,25,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.2	25
MERCK SHARP & DOHME CORP. US Patent					Assay Description A 20 ul reaction mixture contains 10 mM TriHCl, pH 7.2, 0.5 nM GST tagged IRAK4 (SignalChem), 100 nM fluorescent peptide substrate (RP7030, Molecul...				US Patent US9221809 (2015) BindingDB Entry DOI: 10.7270/Q23B5XZM
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