Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM312068'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM312068 (2-[(2-Aminoethyl)amino]-N-(3-carbamoyl-1-methyl-1H...) Show SMILES Cn1cc(NC(=O)c2ccc3cnc(NCCN)nn23)c(n1)C(N)=O Show InChI InChI=1S/C14H17N9O2/c1-22-7-9(11(20-22)12(16)24)19-13(25)10-3-2-8-6-18-14(17-5-4-15)21-23(8)10/h2-3,6-7H,4-5,15H2,1H3,(H2,16,24)(H,17,21)(H,19,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...				US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J
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