Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM319554'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM319554 (4-(1-methyl-1H-pyrazol-4-yl)-1-{[(2S)-5-oxopyrroli...) Show SMILES CC(C)Oc1cc2c(OC[C@@H]3CCC(=O)N3)ncc(-c3cnn(C)c3)c2cc1C(N)=O |r| Show InChI InChI=1S/C22H25N5O4/c1-12(2)31-19-7-16-15(6-17(19)21(23)29)18(13-8-25-27(3)10-13)9-24-22(16)30-11-14-4-5-20(28)26-14/h6-10,12,14H,4-5,11H2,1-3H3,(H2,23,29)(H,26,28)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description This is an in vitro assay to measure IRAK4 enzymatic activity utilizing the DELFIA (Dissociation-Enhanced Lanthanide Fluorescent Immunoassay, Perkin-...				US Patent US10174000 (2019) BindingDB Entry DOI: 10.7270/Q27S7QWQ
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM319554 (4-(1-methyl-1H-pyrazol-4-yl)-1-{[(2S)-5-oxopyrroli...) Show SMILES CC(C)Oc1cc2c(OC[C@@H]3CCC(=O)N3)ncc(-c3cnn(C)c3)c2cc1C(N)=O |r| Show InChI InChI=1S/C22H25N5O4/c1-12(2)31-19-7-16-15(6-17(19)21(23)29)18(13-8-25-27(3)10-13)9-24-22(16)30-11-14-4-5-20(28)26-14/h6-10,12,14H,4-5,11H2,1-3H3,(H2,23,29)(H,26,28)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description This is an in vitro assay to measure IRAK4 enzymatic activity utilizing the DELFIA (Dissociation-Enhanced Lanthanide Fluorescent Immunoassay, Perkin-...				US Patent US10174000 (2019) BindingDB Entry DOI: 10.7270/Q27S7QWQ
					More data for this Ligand-Target Pair