Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM319558'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM319558 (4-(5-Methyl-1,3-oxazol-2-yl)-1-{[(2S)-5-oxopyrroli...) Show SMILES CC(C)Oc1cc2c(OC[C@@H]3CCC(=O)N3)ncc(-c3ncc(C)o3)c2cc1C(N)=O |r| Show InChI InChI=1S/C22H24N4O5/c1-11(2)30-18-7-15-14(6-16(18)20(23)28)17(22-24-8-12(3)31-22)9-25-21(15)29-10-13-4-5-19(27)26-13/h6-9,11,13H,4-5,10H2,1-3H3,(H2,23,28)(H,26,27)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description This is an in vitro assay to measure IRAK4 enzymatic activity utilizing the DELFIA (Dissociation-Enhanced Lanthanide Fluorescent Immunoassay, Perkin-...				US Patent US10174000 (2019) BindingDB Entry DOI: 10.7270/Q27S7QWQ
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM319558 (4-(5-Methyl-1,3-oxazol-2-yl)-1-{[(2S)-5-oxopyrroli...) Show SMILES CC(C)Oc1cc2c(OC[C@@H]3CCC(=O)N3)ncc(-c3ncc(C)o3)c2cc1C(N)=O |r| Show InChI InChI=1S/C22H24N4O5/c1-11(2)30-18-7-15-14(6-16(18)20(23)28)17(22-24-8-12(3)31-22)9-25-21(15)29-10-13-4-5-19(27)26-13/h6-9,11,13H,4-5,10H2,1-3H3,(H2,23,28)(H,26,27)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description This is an in vitro assay to measure IRAK4 enzymatic activity utilizing the DELFIA (Dissociation-Enhanced Lanthanide Fluorescent Immunoassay, Perkin-...				US Patent US10174000 (2019) BindingDB Entry DOI: 10.7270/Q27S7QWQ
					More data for this Ligand-Target Pair