Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM319573'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM319573 (4-(((2S,3R)-3-ethyl-5-oxopyrrolidin-2-yl)methoxy)-...) Show SMILES CC[C@@H]1CC(=O)N[C@@H]1COc1cncc2cc(C(N)=O)c(OC)cc12 |r| Show InChI InChI=1S/C18H21N3O4/c1-3-10-5-17(22)21-14(10)9-25-16-8-20-7-11-4-13(18(19)23)15(24-2)6-12(11)16/h4,6-8,10,14H,3,5,9H2,1-2H3,(H2,19,23)(H,21,22)/t10-,14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description This is an in vitro assay to measure IRAK4 enzymatic activity utilizing the DELFIA (Dissociation-Enhanced Lanthanide Fluorescent Immunoassay, Perkin-...				US Patent US10174000 (2019) BindingDB Entry DOI: 10.7270/Q27S7QWQ
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM319573 (4-(((2S,3R)-3-ethyl-5-oxopyrrolidin-2-yl)methoxy)-...) Show SMILES CC[C@@H]1CC(=O)N[C@@H]1COc1cncc2cc(C(N)=O)c(OC)cc12 |r| Show InChI InChI=1S/C18H21N3O4/c1-3-10-5-17(22)21-14(10)9-25-16-8-20-7-11-4-13(18(19)23)15(24-2)6-12(11)16/h4,6-8,10,14H,3,5,9H2,1-2H3,(H2,19,23)(H,21,22)/t10-,14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description This is an in vitro assay to measure IRAK4 enzymatic activity utilizing the DELFIA (Dissociation-Enhanced Lanthanide Fluorescent Immunoassay, Perkin-...				US Patent US10174000 (2019) BindingDB Entry DOI: 10.7270/Q27S7QWQ
					More data for this Ligand-Target Pair