Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM50246810'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM50246810 (CHEMBL4078625) Show SMILES CN(C)[C@H]1CC[C@@H](CC1)Nc1ncnc2[nH]cc(C3CCC3)c12 |r,wU:6.9,wD:3.2,(14.47,-18.02,;13.14,-17.24,;13.15,-15.7,;11.81,-18.01,;10.48,-17.24,;9.14,-18,;9.15,-19.55,;10.47,-20.31,;11.8,-19.55,;7.81,-20.32,;7.81,-21.86,;9.15,-22.62,;9.15,-24.17,;7.82,-24.94,;6.49,-24.17,;5.02,-24.65,;4.1,-23.41,;5,-22.15,;4.52,-20.69,;5.2,-19.31,;3.82,-18.63,;3.13,-20,;6.48,-22.62,)| Show InChI InChI=1S/C18H27N5/c1-23(2)14-8-6-13(7-9-14)22-18-16-15(12-4-3-5-12)10-19-17(16)20-11-21-18/h10-14H,3-9H2,1-2H3,(H2,19,20,21,22)/t13-,14-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant full length His-tagged human IRAK4 expressed in baculovirus expression system using 5-FAM-IPTSPITTTYFFFKKK-COOH as substrat...				J Med Chem 60: 10071-10091 (2017) Article DOI: 10.1021/acs.jmedchem.7b01290 BindingDB Entry DOI: 10.7270/Q2T72KWX
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM50246810 (CHEMBL4078625) Show SMILES CN(C)[C@H]1CC[C@@H](CC1)Nc1ncnc2[nH]cc(C3CCC3)c12 |r,wU:6.9,wD:3.2,(14.47,-18.02,;13.14,-17.24,;13.15,-15.7,;11.81,-18.01,;10.48,-17.24,;9.14,-18,;9.15,-19.55,;10.47,-20.31,;11.8,-19.55,;7.81,-20.32,;7.81,-21.86,;9.15,-22.62,;9.15,-24.17,;7.82,-24.94,;6.49,-24.17,;5.02,-24.65,;4.1,-23.41,;5,-22.15,;4.52,-20.69,;5.2,-19.31,;3.82,-18.63,;3.13,-20,;6.48,-22.62,)| Show InChI InChI=1S/C18H27N5/c1-23(2)14-8-6-13(7-9-14)22-18-16-15(12-4-3-5-12)10-19-17(16)20-11-21-18/h10-14H,3-9H2,1-2H3,(H2,19,20,21,22)/t13-,14-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of IRAK4 in human KARPAS299 cells assessed as reduction in IL-1 stimulated IRAK4 phosphorylation at Thr345/Ser346 residues preincubated fo...				J Med Chem 60: 10071-10091 (2017) Article DOI: 10.1021/acs.jmedchem.7b01290 BindingDB Entry DOI: 10.7270/Q2T72KWX
					More data for this Ligand-Target Pair