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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Interleukin-5' and Ligand = 'BDBM50424123'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-5


(Mus musculus)
BDBM50424123
PNG
(CHEMBL2316358)
Show SMILES Oc1ccc(cc1)C(=O)\C=C\c1c(O)cccc1OCC1CCCCC1
Show InChI InChI=1S/C22H24O4/c23-18-11-9-17(10-12-18)20(24)14-13-19-21(25)7-4-8-22(19)26-15-16-5-2-1-3-6-16/h4,7-14,16,23,25H,1-3,5-6,15H2/b14-13+
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.26E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 in mouse pro-B Y16 cells after 48 hrs by WST1 assay


Eur J Med Chem 59: 31-8 (2013)


Article DOI: 10.1016/j.ejmech.2012.11.007
BindingDB Entry DOI: 10.7270/Q2PV6MP4
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)
BDBM50424123
PNG
(CHEMBL2316358)
Show SMILES Oc1ccc(cc1)C(=O)\C=C\c1c(O)cccc1OCC1CCCCC1
Show InChI InChI=1S/C22H24O4/c23-18-11-9-17(10-12-18)20(24)14-13-19-21(25)7-4-8-22(19)26-15-16-5-2-1-3-6-16/h4,7-14,16,23,25H,1-3,5-6,15H2/b14-13+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.26E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of mouse IL5-mediated mouse Y16 cell proliferation after 48 hrs by WST1 assay


Bioorg Med Chem 23: 2498-504 (2015)


Article DOI: 10.1016/j.bmc.2015.03.045
BindingDB Entry DOI: 10.7270/Q25D8TJF
More data for this
Ligand-Target Pair