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Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-5' and Ligand = 'BDBM50433117'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-5


(Mus musculus)
BDBM50433117
PNG
(CHEMBL2377398)
Show SMILES Clc1ccc(cc1)C(=O)CCc1coc2cccc(OCC3CCCCC3)c2c1=O
Show InChI InChI=1S/C25H25ClO4/c26-20-12-9-18(10-13-20)21(27)14-11-19-16-30-23-8-4-7-22(24(23)25(19)28)29-15-17-5-2-1-3-6-17/h4,7-10,12-13,16-17H,1-3,5-6,11,14-15H2
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition interleukin-5 in mouse Y16 cells after 48 hrs by WST-1 assay


Bioorg Med Chem 21: 2543-50 (2013)


Article DOI: 10.1016/j.bmc.2013.02.037
BindingDB Entry DOI: 10.7270/Q2RR20MV
More data for this
Ligand-Target Pair