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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-8 receptors, CXCR2' and Ligand = 'BDBM50213763'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-8 receptors, CXCR2


(Homo sapiens (Human))
BDBM50213763
PNG
(3-(biphenyl-2-ylamino)-7-chloro-1,1-dioxo-1,4-dihy...)
Show SMILES Oc1cc(Cl)cc2c1N=C(Nc1ccccc1-c1ccccc1)NS2(=O)=O |t:9|
Show InChI InChI=1S/C19H14ClN3O3S/c20-13-10-16(24)18-17(11-13)27(25,26)23-19(22-18)21-15-9-5-4-8-14(15)12-6-2-1-3-7-12/h1-11,24H,(H2,21,22,23)
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 230n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CXCR2 receptor expressed in CHOK1 cells assessed as human IL8-induced calcium mobilization by FLIPR


Bioorg Med Chem Lett 17: 3864-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.011
BindingDB Entry DOI: 10.7270/Q21C1WKG
More data for this
Ligand-Target Pair