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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-8 receptors, CXCR2' and Ligand = 'BDBM50248592'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-8 receptors, CXCR2


(Homo sapiens (Human))
BDBM50248592
PNG
((R)-3-(4-(1-(2,3-dihydro-1H-inden-5-yl)-2,2-dimeth...)
Show SMILES CN(C)C(=O)c1cccc(Nc2nsnc2N[C@@H](c2ccc3CCCc3c2)C(C)(C)C)c1O |r|
Show InChI InChI=1S/C25H31N5O2S/c1-25(2,3)21(17-13-12-15-8-6-9-16(15)14-17)27-23-22(28-33-29-23)26-19-11-7-10-18(20(19)31)24(32)30(4)5/h7,10-14,21,31H,6,8-9H2,1-5H3,(H,26,28)(H,27,29)/t21-/m0/s1
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PC cid
PC sid
UniChem
Article
PubMed
1.00E+4n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Displacement of IL8 from CXCR2 receptor (unknown origin)


Bioorg Med Chem Lett 19: 1434-7 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.027
BindingDB Entry DOI: 10.7270/Q2833RW1
More data for this
Ligand-Target Pair