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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Intermediate conductance calcium-activated potassium channel protein 4' and Ligand = 'BDBM314285'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Intermediate conductance calcium-activated potassium channel protein 4


(Homo sapiens (Human))
BDBM314285
PNG
(US9611232, Example 17)
Show SMILES NC(=O)CN1[C@@H](c2ccccc2F)C(OC1=O)(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C23H19FN2O3/c24-19-14-8-7-13-18(19)21-23(16-9-3-1-4-10-16,17-11-5-2-6-12-17)29-22(28)26(21)15-20(25)27/h1-14,21H,15H2,(H2,25,27)/t21-/m0/s1
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US Patent
n/an/a 15n/an/an/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp...


US Patent US9611232 (2017)


BindingDB Entry DOI: 10.7270/Q2P84DZM
More data for this
Ligand-Target Pair